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4.
Nefrologia (Engl Ed) ; 40(3): 279-286, 2020.
Article in English, Spanish | MEDLINE | ID: covidwho-820202

ABSTRACT

Dialysis patients are a risk group for SARS-CoV-2 infection and possibly further complications, but we have little information. The aim of this paper is to describe the experience of the first month of the SARS-CoV-2 pandemic in a hospital haemodialysis (HD) unit serving the district of Madrid with the second highest incidence of COVID-19 (almost 1,000 patients in 100,000h). In the form of a diary, we present the actions undertaken, the incidence of COVID-19 in patients and health staff, some clinical characteristics and the results of screening all the patients in the unit. We started with 90 patients on HD: 37 (41.1%) had COVID-19, of whom 17 (45.9%) were diagnosed through symptoms detected in triage or during the session, and 15 (40.5%) through subsequent screening of those who, until that time, had not undergone SARS-CoV-2 PCR testing. Fever was the most frequent symptom, 50% had lymphopenia and 18.4% <95% O2 saturation. Sixteen (43.2%) patients required hospital admission and 6 (16.2%) died. We found a cluster of infection per shift and also among those using public transport. In terms of staff, of the 44 people involved, 15 (34%) had compatible symptoms, 4 (9%) were confirmed as SARS-CoV-2 PCR cases by occupational health, 9 (20%) required some period of sick leave, temporary disability to work (ILT), and 5 were considered likely cases. CONCLUSIONS: We detected a high prevalence of COVID-19 with a high percentage detected by screening; hence the need for proactive diagnosis to stop the pandemic. Most cases are managed as outpatients, however severe symptoms are also appearing and mortality to date is 16.2%. In terms of staff, 20% have required sick leave in relation to COVID-19.


Subject(s)
Asymptomatic Infections/epidemiology , Betacoronavirus , Coronavirus Infections/epidemiology , Health Personnel/statistics & numerical data , Hemodialysis Units, Hospital/statistics & numerical data , Pandemics , Pneumonia, Viral/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , COVID-19 , Clinical Protocols , Coronavirus Infections/diagnosis , Coronavirus Infections/drug therapy , Female , Health Personnel/organization & administration , Hemodialysis Units, Hospital/organization & administration , Humans , Incidence , Lymphopenia/epidemiology , Male , Middle Aged , Pneumonia, Viral/diagnosis , Pneumonia, Viral/drug therapy , Prevalence , SARS-CoV-2 , Spain/epidemiology , Symptom Assessment , Time Factors , Triage/methods , Young Adult
5.
J Thromb Thrombolysis ; 51(1): 237-242, 2021 Jan.
Article in English | MEDLINE | ID: covidwho-636047

ABSTRACT

Coronavirus disease 2019 (COVID-19) could predispose to both venous and arterial thromboembolism, in an exaggerated immune response to the virus, especially in severe patients. Even though aortic clots are a rare entity, the pro-coagulant nature of COVID-19 is associated with thrombosis in atypical locations and should be considered in patients with severe abnormalities in coagulation parameters. We describe a series of three cases of aortic thrombi diagnosed by computerized tomography (CT) angiography in patients with confirmed SARS-CoV-2 infection.


Subject(s)
Anticoagulants/administration & dosage , Aorta/diagnostic imaging , Aortic Diseases , COVID-19 , Thrombosis , Aged , Anticoagulants/classification , Aortic Diseases/diagnosis , Aortic Diseases/etiology , Aortic Diseases/physiopathology , COVID-19/blood , COVID-19/complications , COVID-19/diagnosis , COVID-19/therapy , Computed Tomography Angiography/methods , Diagnosis, Differential , Fibrin Fibrinogen Degradation Products/analysis , Humans , Ischemic Stroke/diagnosis , Ischemic Stroke/etiology , Ischemic Stroke/physiopathology , Male , Middle Aged , Pulmonary Embolism/diagnostic imaging , Pulmonary Embolism/etiology , Pulmonary Embolism/therapy , SARS-CoV-2/isolation & purification , Severity of Illness Index , Thrombosis/blood , Thrombosis/diagnosis , Thrombosis/drug therapy , Thrombosis/etiology , Tomography, X-Ray Computed/methods , Treatment Outcome
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